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If Helix Health results are negative, is regular cancer and cholesterol screening still needed?

Yes, even if your genetic test results are negative, regular cancer surveillance including (but not limited to) mammograms, colonoscopies, PSA testing and lipid screening (or cholesterol testing) are still recommended.

Yes, even if your genetic test results are negative, regular cancer surveillance including (but not limited to) mammograms, colonoscopies, PSA testing and lipid screening (or cholesterol testing) are still recommended. Here's why:

1. Genetic testing limitations: Helix Health genetic testing includes eleven genes that are associated with just three medical conditions (two high-risk cancer syndromes and a genetic form of very high cholesterol). This is a very small subset of genes associated with disease. Helix Health genetic testing does not cover all possible genetic variants or factors that contribute to cancer or heart disease development. Therefore, a negative genetic test result does not guarantee complete freedom from the risk of developing these conditions.

2. Population risk: Most cancer and heart disease occurs in individuals who do not have an identifiable hereditary genetic variant. For example, the majority of cancers are sporadic, meaning they arise without a known genetic cause. Regular mammograms are an effective screening tool for detecting breast cancer in the general population, regardless of genetic test results.

3. Age and risk factors: Age and other risk factors for cancer and heart disease play a significant role in determining the appropriate screening guidelines. These guidelines are not solely based on genetic test results but take into account various factors that contribute to disease risk.

4. Early detection: Cancer and heart disease screening can identify changes that may indicate the presence of a condition, even before symptoms are noticeable. Detecting disease at an early stage greatly improves the chances of successful treatment and better outcomes.

It is important for participants to consult with their healthcare providers to determine the appropriate screening and surveillance plan based on their individual risk factors. These risk factors include age, family history and personal medical history. Regular conversations with ahealthcare provider will help ensure that the most appropriate and comprehensive cancer and heart disease screening and prevention.